Allelic Variants

There are no related allelic variants
Related diseases of KIF 3E5AA_VX6 (PDB code: 3E5A, chain A)
Number of involved diseases in the family 93
Number of FGFR3 related diseases 14
All kinase in this family  FGFR3
Allelic
Variants		 Disease Description Involved kinases
(This family)		 Inhibitor of
Involved Kinases		 Search
Disease
n/aMeaslesAKT2, CDK2, CHUK, GSK3B,
IRAK4, JAK2, JAK3, PRKCQ		44Link
n/aEpstein-Barr virus infectionAKT2, CDC2, CDK2, CHUK,
GSK3B, JAK3, RIPK1, SYK		23Link
Prostate cancerAKT2, CDK2, CHUK, FGFR1,
FGFR2, GSK3B		23Link
n/aTuberculosisAKT2, IRAK4, JAK2, PLK3, SYK16Link
LeukemiaABL1, ABL2, AKT2, CHUK, JAK221Link
NeuroblastomaALK, NTRK1, NTRK2, NTRK35Link
Lung cancerAKT2, ALK, CDK2, CHUK17Link
n/aInfluenza AAKT2, GSK3B, IRAK4, JAK221Link
n/aHerpes simplex infectionCDC2, CDK2, CHUK, JAK228Link
n/aToxoplasmosisAKT2, CHUK, IRAK4, JAK218Link
n/aHepatitis CAKT2, CHUK, GSK3B, RIPK112Link
n/aChagas diseaseAKT2, CHUK, IRAK45Link
Pfeiffer syndromeFGFR1, FGFR22Link
LADD syndromeFGFR2, FGFR32Link
Jackson-Weiss syndromeFGFR1, FGFR22Link
MelanomaAKT2, FGFR13Link
Diabetes mellitusAKT2, PRKCD10Link
n/aShigellosisABL1, CHUK8Link
n/aViral myocarditisABL1, ABL25Link
n/aLeishmaniasisIRAK4, JAK214Link
Crouzon syndromeFGFR2, FGFR32Link
SCIDJAK3, LCK9Link
n/aSalmonella infectionPKN1, PKN22Link
n/aImmunodeficienciesJAK3, LCK9Link
n/aMedullary thyroid carcinomaNTRK1, RET5Link
n/aThyroid cancerNTRK1, RET5Link
Hypogonadotropic hypogonadismFGFR12Link
n/aEpithelial cell signaling in Helicobacter pylori infectionCHUK3Link
n/aAgammaglobulinemia and isolated hormone deficiencyBTK2Link
AgammaglobulinemiaBTK2Link
n/aAgammaglobulinemiasBTK2Link
n/aPituitary DwarfismBTK2Link
n/aCocoon syndromeCHUK3Link
n/aMaturity onset diabetes of the youngBLK2Link
n/aEpileptic encephalopathyCDKL51Link
n/aAngelman syndrome-likeCDKL51Link
n/aEarly infantile epileptic encephalopathyCDKL51Link
n/aCocaine addictionCDK51Link
n/aPrader-Willi and Angelman syndromesCDKL51Link
Colon cancerAURKA64Link
Osteoglophonic dysplasiaFGFR12Link
Multiple endocrine neoplasiaRET3Link
Central hypoventilation syndromeRET3Link
n/aFamilial partial lipodystrophyAKT21Link
Ovarian cancerAKT21Link
n/aPathogenic Escherichia coli infectionABL15Link
Renal agenesisRET3Link
PheochromocytomaRET3Link
n/aCongenital central hypoventilation syndromeRET3Link
Hirschsprung diseaseRET3Link
n/aObesityNTRK23Link
Hypoinsulinemic hypoglycemiaAKT21Link
n/aAlcoholismNTRK23Link
n/aGlycogen storage diseasesPHKG21Link
n/aCirrhosis due to liver phosphorylase kinase deficiencyPHKG21Link
n/aRenal agenesis and Renal adysplasiaRET3Link
n/aType I diabetes mellitusPRKCQ10Link
Glycogen storage diseasePHKG21Link
TrigonocephalyFGFR12Link
n/aMyeloproliferative disorderJAK214Link
n/aSpermatocytic seminomaFGFR32Link
n/aThanatophoric dysplasiaFGFR32Link
n/aNevusFGFR32Link
n/aMuenke syndromeFGFR32Link
Colorectal cancerFGFR32Link
n/aHypochondroplasiaFGFR32Link
n/aCancer progression/metastasisFGFR42Link
n/aBasal cell carcinomaGSK3B6Link
n/aBudd-Chiari syndromeJAK214Link
MyelofibrosisJAK214Link
Polycythemia veraJAK214Link
IRAK4 deficiencyIRAK41Link
n/aPertussisIRAK41Link
ThrombocythemiaJAK214Link
n/aInvasive pneumococcal diseaseIRAK41Link
n/aCervical cancerFGFR32Link
n/aAchondroplasiaFGFR32Link
Beare-Stevenson cutis gyrata syndromeFGFR22Link
Bent bone dysplasia syndromeFGFR22Link
Apert syndromeFGFR22Link
n/aAntley-Bixler syndrome without genital anomalies or disordered steroidogenesisFGFR22Link
n/aInsensitivity to painNTRK15Link
Kallmann syndromeFGFR12Link
Gastric cancerFGFR22Link
Craniofacial-skeletal-dermatologic dysplasiaFGFR22Link
CraniosynostosisFGFR22Link
n/aFGFR3-related short limb skeletal dysplasiasFGFR32Link
n/aCATSHL syndromeFGFR32Link
n/aBladder cancerFGFR32Link
n/aMultiple myelomaFGFR32Link
n/aSaethre-Chotzen syndromeFGFR22Link
ScaphocephalyFGFR22Link
n/aScaphocephaly and Axenfeld-Rieger anomalyFGFR22Link