KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 3EFWA_AK8 (PDB code: 3EFW, chain A)
Number of involved diseases in the family	105
Number of FGFR3 related diseases	14

All kinase in this family FGFR3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	CDK2, EIF2AK2, JAK1, JAK3, MAP2K4, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9, PRKACA, PRKACB, PRKX, RIPK1, SYK	5	Link
n/a	Hepatitis C	BRAF, EGFR, EIF2AK2, JAK1, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9, RAF1, RIPK1	14	Link
n/a	Influenza A	EIF2AK2, JAK1, JAK2, MAP2K4, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9, RAF1	3	Link
n/a	Tuberculosis	JAK1, JAK2, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9, PLK3, RAF1, SYK	3	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, MAP2K4, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9	3	Link
	Prostate cancer	BRAF, CDK2, CHEK2, EGFR, FGFR1, FGFR2, RAF1	13	Link
n/a	Herpes simplex infection	CDK2, EIF2AK2, JAK1, JAK2, MAPK10, MAPK8, MAPK9	3	Link
n/a	Toxoplasmosis	JAK1, JAK2, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9	3	Link
	Leukemia	ABL1, ABL2, BRAF, CDK4, JAK2, RAF1, RPS6KB1	15	Link
n/a	Measles	CDK2, CDK4, EIF2AK2, JAK1, JAK2, JAK3, PRKCQ	4	Link
n/a	Chagas disease	MAP2K4, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9	3	Link
n/a	Shigellosis	ABL1, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9	5	Link
	Lung cancer	ALK, BRAF, CDK2, CDK4, EGFR, PTK2	13	Link
n/a	Alcoholism	BRAF, CAMKK1, CAMKK2, NTRK2, PRKACA, RAF1	13	Link
	Melanoma	BRAF, CDK4, EGFR, FGFR1, RAF1	13	Link
n/a	Pertussis	MAPK10, MAPK12, MAPK13, MAPK8, MAPK9	3	Link
n/a	Salmonella infection	MAPK10, MAPK12, MAPK13, MAPK8, MAPK9	3	Link
n/a	Cardiomyopathy	MYLK2, PRKAA1, PRKACA, PRKACB, PRKX	2	Link
n/a	Cocaine addiction	CDK5, PRKACA, PRKACB, PRKX	2	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	2	Link
n/a	Leishmaniasis	JAK1, JAK2, MAPK12, MAPK13	2	Link
n/a	Amoebiasis	PRKACA, PRKACB, PRKX, PTK2	3	Link
n/a	Vibrio cholerae infection	PRKACA, PRKACB, PRKX	2	Link
n/a	Cervical cancer	CDK4, EGFR, FGFR3	2	Link
n/a	Prion diseases	PRKACA, PRKACB, PRKX	2	Link
	Diabetes mellitus	MAPK10, MAPK8, MAPK9	3	Link
n/a	Thyroid cancer	BRAF, NTRK1, RET	13	Link
n/a	Early infantile epileptic encephalopathy	CDKL5, MAPK10	3	Link
n/a	Malignant melanoma	BRAF, CDK4	13	Link
n/a	Viral myocarditis	ABL1, ABL2	4	Link
	LADD syndrome	FGFR2, FGFR3	2	Link
n/a	Glioma	CDK4, EGFR	2	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	2	Link
	Pfeiffer syndrome	FGFR1, FGFR2	2	Link
n/a	Bladder cancer	EGFR, FGFR3	2	Link
	Crouzon syndrome	FGFR2, FGFR3	2	Link
	Gastric cancer	EGFR, FGFR2	2	Link
n/a	Epileptic encephalopathy	CDKL5, MAPK10	3	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	2	Link
	LEOPARD syndrome	BRAF, RAF1	13	Link
	Colorectal cancer	BRAF, FGFR3	13	Link
n/a	Immunodeficiencies	JAK3, LCK	13	Link
	Adenocarcinoma of lung	BRAF, EGFR	13	Link
	SCID	JAK3, LCK	13	Link
	Noonan syndrome	BRAF, RAF1	13	Link
n/a	Amyotrophic lateral sclerosis	MAPK12, MAPK13	2	Link
n/a	Prader-Willi and Angelman syndromes	CDKL5	1	Link
	Li-Fraumeni syndrome	CHEK2	1	Link
n/a	Choriocarcinoma	EGFR	2	Link
n/a	Laryngeal cancer	EGFR	2	Link
n/a	Pathogenic Escherichia coli infection	ABL1	4	Link
n/a	Noonan syndrome and related disorders	BRAF	13	Link
	Hypogonadotropic hypogonadism	FGFR1	2	Link
	Cardiofaciocutaneous syndrome	BRAF	13	Link
	Colon cancer	AURKA	8	Link
	Osteosarcoma	CHEK2	1	Link
	Breast cancer	CHEK2	1	Link
	Osteoglophonic dysplasia	FGFR1	2	Link
n/a	Oral cancer	EGFR	2	Link
n/a	Angelman syndrome-like	CDKL5	1	Link
n/a	Maturity onset diabetes of the young	BLK	2	Link
n/a	Esophageal cancer	EGFR	2	Link
	Craniosynostosis	FGFR2	2	Link
	Trigonocephaly	FGFR1	2	Link
n/a	Short rib-polydactyly syndorme	NEK1	1	Link
n/a	Insensitivity to pain	NTRK1	2	Link
n/a	Obesity	NTRK2	2	Link
	REtinitis pigmentosa	MAK	1	Link
	Thrombocythemia	JAK2	2	Link
n/a	Budd-Chiari syndrome	JAK2	2	Link
	Myelofibrosis	JAK2	2	Link
n/a	Myeloproliferative disorder	JAK2	2	Link
n/a	Type I diabetes mellitus	PRKCQ	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	2	Link
n/a	Basal cell carcinoma	STK36	2	Link
	Venous malformations	TEK	35	Link
n/a	Rheumatoid arthritis	TEK	35	Link
	Renal agenesis	RET	2	Link
	Pheochromocytoma	RET	2	Link
	Hirschsprung disease	RET	2	Link
n/a	Congenital central hypoventilation syndrome	RET	2	Link
	Central hypoventilation syndrome	RET	2	Link
	Multiple endocrine neoplasia	RET	2	Link
	Polycythemia vera	JAK2	2	Link
	Lymphoproliferative syndrome	ITK	2	Link
n/a	Saethre-Chotzen syndrome	FGFR2	2	Link
	Scaphocephaly	FGFR2	2	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	2	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	2	Link
	Bent bone dysplasia syndrome	FGFR2	2	Link
	Kallmann syndrome	FGFR1	2	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	2	Link
	Apert syndrome	FGFR2	2	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	2	Link
n/a	Multiple myeloma	FGFR3	1	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	1	Link
n/a	Thanatophoric dysplasia	FGFR3	1	Link
n/a	Cancer progression/metastasis	FGFR4	2	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	1	Link
n/a	Spermatocytic seminoma	FGFR3	1	Link
n/a	Nevus	FGFR3	1	Link
n/a	CATSHL syndrome	FGFR3	1	Link
n/a	Achondroplasia	FGFR3	1	Link
n/a	Hypochondroplasia	FGFR3	1	Link
n/a	Muenke syndrome	FGFR3	1	Link

BioXGEM.

KIDFamMap

Allelic Variants