Allelic Variants

There are no related allelic variants
Related diseases of KIF 3A4OX_STU (PDB code: 3A4O, chain X)
Number of involved diseases in the family 88
Number of LYN related diseases 2
All kinase in this family  LYN
Allelic
Variants		 Disease Description Involved kinases
(This family)		 Inhibitor of
Involved Kinases		 Search
Disease
Prostate cancerCDK2, EGFR, EPHB2, FGFR1,
FGFR2, PDGFRA, PDGFRB, PDPK1		44Link
n/aEpstein-Barr virus infectionCDC2, CDK2, FGR, LYN,
MAPK14, SYK		15Link
n/aEpithelial cell signaling in Helicobacter pylori infectionCSK, EGFR, LYN, MAPK14, SRC41Link
LeukemiaABL1, ABL2, JAK2, KIT,
PDGFRB		15Link
MelanomaEGFR, FGFR1, PDGFRA, PDGFRB41Link
n/aTuberculosisJAK2, MAPK14, SRC, SYK21Link
n/aBladder cancerDAPK1, EGFR, FGFR339Link
n/aMeaslesCDK2, FYN, JAK214Link
n/aGliomaEGFR, PDGFRA, PDGFRB41Link
n/aHerpes simplex infectionCDC2, CDK2, JAK214Link
Lung cancerCDK2, EGFR, PTK242Link
n/aInfluenza AJAK2, MAPK14, PRKCA59Link
n/aPathogenic Escherichia coli infectionABL1, FYN, PRKCA61Link
n/aShigellosisABL1, MAPK14, SRC20Link
n/aViral myocarditisABL1, ABL2, FYN13Link
n/aCervical cancerEGFR, FGFR338Link
n/aSalmonella infectionMAPK14, PKN112Link
n/aLeishmaniasisJAK2, MAPK1411Link
n/aHepatitis CEGFR, MAPK1439Link
n/aToxoplasmosisJAK2, MAPK1411Link
Crouzon syndromeFGFR2, FGFR38Link
LADD syndromeFGFR2, FGFR38Link
Pfeiffer syndromeFGFR1, FGFR29Link
Jackson-Weiss syndromeFGFR1, FGFR29Link
Gastric cancerEGFR, FGFR239Link
Gastrointestinal stromal tumorKIT, PDGFRA12Link
n/aChoriocarcinomaCSF1R, EGFR43Link
n/aMyeloproliferative disorderJAK2, PDGFRB12Link
n/aImmunodeficienciesLCK, ZAP7011Link
n/aAmoebiasisPRKCA, PTK257Link
Kallmann syndromeFGFR19Link
n/aPituitary DwarfismBTK5Link
n/aAgammaglobulinemiasBTK5Link
n/aAntley-Bixler syndrome without genital anomalies or disordered steroidogenesisFGFR28Link
TrigonocephalyFGFR19Link
Apert syndromeFGFR28Link
n/aAgammaglobulinemia and isolated hormone deficiencyBTK5Link
AgammaglobulinemiaBTK5Link
Hypogonadotropic hypogonadismFGFR19Link
Osteoglophonic dysplasiaFGFR19Link
n/aOral cancerEGFR38Link
n/aMaturity onset diabetes of the youngBLK8Link
Fibrodysplasia ossificans progressivaACVR13Link
n/aEsophageal cancerEGFR38Link
n/aLeukoencephalopathy, diffuse hereditary, with spheroidsCSF1R13Link
Beare-Stevenson cutis gyrata syndromeFGFR28Link
Adenocarcinoma of lungEGFR38Link
n/aCocaine addictionCDK55Link
n/aLaryngeal cancerEGFR38Link
n/aSaethre-Chotzen syndromeFGFR28Link
Bent bone dysplasia syndromeFGFR28Link
SCIDLCK11Link
REtinitis pigmentosaMAK1Link
Mastocytosis with associated hematologic disorderKIT12Link
Mast cell leukemiaKIT12Link
ThrombocythemiaJAK210Link
PiebaldismKIT12Link
n/aGerm cell tumorsKIT12Link
n/aAmyotrophic lateral sclerosisMAPK141Link
n/aPertussisMAPK141Link
Diabetes mellitusPRKCE11Link
Colon cancerSRC19Link
Selective T-cell defectZAP7010Link
n/aPituitary tumorPRKCA55Link
n/aAfrican trypanosomiasisPRKCA55Link
n/aChagas diseaseMAPK141Link
n/aHypereosinophilic syndromePDGFRA10Link
n/aVibrio cholerae infectionPRKCA55Link
MyelofibrosisJAK210Link
n/aBudd-Chiari syndromeJAK210Link
n/aFGFR3-related short limb skeletal dysplasiasFGFR37Link
n/aCATSHL syndromeFGFR37Link
n/aAchondroplasiaFGFR37Link
n/aMultiple myelomaFGFR37Link
n/aScaphocephaly and Axenfeld-Rieger anomalyFGFR28Link
Craniofacial-skeletal-dermatologic dysplasiaFGFR28Link
CraniosynostosisFGFR28Link
ScaphocephalyFGFR28Link
Colorectal cancerFGFR37Link
n/aHypochondroplasiaFGFR37Link
n/aPrion diseasesFYN10Link
n/aEndocrine-cerebroosteodysplasiaICK2Link
Polycythemia veraJAK210Link
n/aCancer progression/metastasisFGFR43Link
n/aThanatophoric dysplasiaFGFR37Link
n/aMuenke syndromeFGFR37Link
n/aNevusFGFR37Link
n/aSpermatocytic seminomaFGFR37Link