Allelic Variants
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There are no related allelic variants
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Number of involved diseases in the family |
124 |
Number of MATK related diseases |
0 |
All kinase in this family
MATK
Allelic Variants |
Disease Description |
Involved kinases (This family) |
Inhibitor of Involved Kinases |
Search Disease |
| Prostate cancer | CDK2, EGFR, EPHB2, ERBB2, FGFR1, FGFR2, MAPK1, PDGFRA, PDGFRB | 45 | Link | n/a | Epstein-Barr virus infection | CDK2, FGR, JAK1, JAK3, LYN, MAPK14, SYK, TYK2 | 19 | Link | n/a | Measles | CDK2, FYN, IRAK4, JAK1, JAK2, JAK3, PRKCQ, TYK2 | 18 | Link | n/a | Tuberculosis | IRAK4, JAK1, JAK2, MAPK1, MAPK14, SRC, SYK | 21 | Link | | Leukemia | ABL1, ABL2, JAK2, KIT, MAPK1, PDGFRB, TGFBR1 | 15 | Link | n/a | Influenza A | IRAK4, JAK1, JAK2, MAPK1, MAPK14, PRKCA, TYK2 | 60 | Link | n/a | Toxoplasmosis | IRAK4, JAK1, JAK2, MAPK1, MAPK14, TYK2 | 12 | Link | | Melanoma | EGFR, FGFR1, MAPK1, PDGFRA, PDGFRB | 42 | Link | n/a | Hepatitis C | EGFR, JAK1, MAPK1, MAPK14, TYK2 | 41 | Link | n/a | Epithelial cell signaling in Helicobacter pylori infection | CSK, EGFR, LYN, MAPK14, SRC | 41 | Link | n/a | Leishmaniasis | IRAK4, JAK1, JAK2, MAPK1, MAPK14 | 12 | Link | n/a | Salmonella infection | MAPK1, MAPK14, PKN1, PKN2 | 13 | Link | n/a | Chagas disease | IRAK4, MAPK1, MAPK14, TGFBR1 | 6 | Link | n/a | Herpes simplex infection | CDK2, JAK1, JAK2, TYK2 | 14 | Link | n/a | Shigellosis | ABL1, MAPK1, MAPK14, SRC | 20 | Link | | Lung cancer | ALK, CDK2, EGFR, ROS1 | 43 | Link | | Diabetes mellitus | INSR, MAPK1, PRKCD, PRKCE | 15 | Link | n/a | Bladder cancer | EGFR, ERBB2, FGFR3 | 38 | Link | | Gastric cancer | EGFR, ERBB2, FGFR2 | 39 | Link | n/a | Pertussis | IRAK4, MAPK1, MAPK14 | 6 | Link | n/a | Viral myocarditis | ABL1, ABL2, FYN | 13 | Link | n/a | Choriocarcinoma | CSF1R, EGFR, ERBB2 | 43 | Link | n/a | Pathogenic Escherichia coli infection | ABL1, FYN, PRKCA | 61 | Link | n/a | Glioma | EGFR, PDGFRA, PDGFRB | 41 | Link | n/a | Immunodeficiencies | JAK3, LCK, ZAP70 | 16 | Link | n/a | Cervical cancer | EGFR, ERBB2, FGFR3 | 38 | Link | | Neuroblastoma | ALK, NTRK2, NTRK3 | 10 | Link | | Adenocarcinoma of lung | EGFR, ERBB2 | 38 | Link | n/a | Myeloproliferative disorder | JAK2, PDGFRB | 12 | Link | n/a | Prion diseases | FYN, MAPK1 | 11 | Link | | Jackson-Weiss syndrome | FGFR1, FGFR2 | 9 | Link | | Pfeiffer syndrome | FGFR1, FGFR2 | 9 | Link | | LADD syndrome | FGFR2, FGFR3 | 8 | Link | | Crouzon syndrome | FGFR2, FGFR3 | 8 | Link | | SCID | JAK3, LCK | 16 | Link | n/a | Pancreatic cancer | ACVR1B, ERBB2 | 3 | Link | n/a | Alcoholism | MAPK1, NTRK2 | 11 | Link | | Gastrointestinal stromal tumor | KIT, PDGFRA | 12 | Link | n/a | Juvenile polyposis syndrome | BMPR1A | 2 | Link | | Kallmann syndrome | FGFR1 | 9 | Link | | Brachydactyly | BMPR1B | 1 | Link | n/a | Polyposis | BMPR1A | 2 | Link | | Trigonocephaly | FGFR1 | 9 | Link | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 8 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 8 | Link | | Apert syndrome | FGFR2 | 8 | Link | | Craniosynostosis | FGFR2 | 8 | Link | | Fibrodysplasia ossificans progressiva | ACVR1 | 3 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 8 | Link | | Bent bone dysplasia syndrome | FGFR2 | 8 | Link | | Osteoglophonic dysplasia | FGFR1 | 9 | Link | n/a | Maturity onset diabetes of the young | BLK | 8 | Link | | Hypogonadotropic hypogonadism | FGFR1 | 9 | Link | n/a | Saethre-Chotzen syndrome | FGFR2 | 8 | Link | | Ovarian cancer | ERBB2 | 2 | Link | | Breast cancer | ERBB2 | 2 | Link | | Endometrial Cancer | ERBB2 | 2 | Link | n/a | Oral cancer | EGFR | 38 | Link | n/a | Laryngeal cancer | EGFR | 38 | Link | n/a | Esophageal cancer | EGFR | 38 | Link | n/a | Cholangiocarcinoma | ERBB2 | 2 | Link | n/a | Leukoencephalopathy, diffuse hereditary, with spheroids | CSF1R | 13 | Link | | Glioblastoma | ERBB2 | 2 | Link | n/a | Chrondrodysplasia | BMPR1B | 1 | Link | n/a | Agammaglobulinemias | BTK | 5 | Link | n/a | Pituitary Dwarfism | BTK | 5 | Link | n/a | Cocaine addiction | CDK5 | 5 | Link | n/a | Agammaglobulinemia and isolated hormone deficiency | BTK | 5 | Link | | Agammaglobulinemia | BTK | 5 | Link | | Colorectal cancer | FGFR3 | 7 | Link | | Scaphocephaly | FGFR2 | 8 | Link | n/a | Pituitary tumor | PRKCA | 55 | Link | n/a | Type I diabetes mellitus | PRKCQ | 8 | Link | n/a | Thyroid cancer | RET | 11 | Link | n/a | Renal agenesis and Renal adysplasia | RET | 11 | Link | n/a | Amoebiasis | PRKCA | 55 | Link | n/a | African trypanosomiasis | PRKCA | 55 | Link | n/a | Congenital myasthenic syndrome | MUSK | 5 | Link | n/a | Myasthenic syndrome | MUSK | 5 | Link | n/a | Obesity | NTRK2 | 9 | Link | n/a | Vibrio cholerae infection | PRKCA | 55 | Link | n/a | Hypereosinophilic syndrome | PDGFRA | 10 | Link | | Hirschsprung disease | RET | 11 | Link | n/a | Congenital central hypoventilation syndrome | RET | 11 | Link | | Loeys-Dietz syndrome | TGFBR1 | 2 | Link | n/a | Familial thoracic aortic aneurysm and dissection | TGFBR1 | 2 | Link | | Multiple self-healing squamous epithelioma | TGFBR1 | 2 | Link | | Selective T-cell defect | ZAP70 | 10 | Link | n/a | Tyrosine kinase 2 deficiency | TYK2 | 8 | Link | n/a | Transient erythroblastopenia of childhood | TEC | 2 | Link | | Colon cancer | SRC | 19 | Link | | Central hypoventilation syndrome | RET | 11 | Link | n/a | Medullary thyroid carcinoma | RET | 11 | Link | | Multiple endocrine neoplasia | RET | 11 | Link | | Renal agenesis | RET | 11 | Link | | Pheochromocytoma | RET | 11 | Link | n/a | Amyotrophic lateral sclerosis | MAPK14 | 1 | Link | | REtinitis pigmentosa | MAK | 1 | Link | n/a | Nevus | FGFR3 | 7 | Link | n/a | Spermatocytic seminoma | FGFR3 | 7 | Link | n/a | Thanatophoric dysplasia | FGFR3 | 7 | Link | n/a | Endocrine-cerebroosteodysplasia | ICK | 2 | Link | n/a | Cancer progression/metastasis | FGFR4 | 3 | Link | n/a | Muenke syndrome | FGFR3 | 7 | Link | n/a | Hypochondroplasia | FGFR3 | 7 | Link | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 8 | Link | n/a | Multiple myeloma | FGFR3 | 7 | Link | n/a | FGFR3-related short limb skeletal dysplasias | FGFR3 | 7 | Link | n/a | Achondroplasia | FGFR3 | 7 | Link | n/a | CATSHL syndrome | FGFR3 | 7 | Link | n/a | Leprechaunism | INSR | 5 | Link | | Rabson-Mendenhall syndrome | INSR | 5 | Link | | Thrombocythemia | JAK2 | 10 | Link | | Piebaldism | KIT | 12 | Link | n/a | Germ cell tumors | KIT | 12 | Link | | Mastocytosis with associated hematologic disorder | KIT | 12 | Link | | Mast cell leukemia | KIT | 12 | Link | | Myelofibrosis | JAK2 | 10 | Link | n/a | Budd-Chiari syndrome | JAK2 | 10 | Link | | Hyperinsulinemic hypoglycemia | INSR | 5 | Link | n/a | Invasive pneumococcal disease | IRAK4 | 4 | Link | | IRAK4 deficiency | IRAK4 | 4 | Link | | Polycythemia vera | JAK2 | 10 | Link | | Lymphoproliferative syndrome | ITK | 6 | Link |
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