KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 1H00A_FAP (PDB code: 1H00, chain A)
Number of involved diseases in the family	75
Number of ROCK2 related diseases	3

All kinase in this family ROCK2

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Measles	CDK2, CDK4, FYN, GSK3B, IRAK4, PRKCQ	55	Link
n/a	Epstein-Barr virus infection	CDK2, FGR, GSK3B, MAPK10, MAPK9	36	Link
	Prostate cancer	CDK2, CHEK2, FGFR2, GSK3B, MAP2K1	36	Link
n/a	Influenza A	GSK3B, IRAK4, MAP2K1, MAPK10, MAPK9	7	Link
n/a	Shigellosis	ABL1, MAPK10, MAPK9, ROCK2, SRC	42	Link
n/a	Tuberculosis	IRAK4, MAPK10, MAPK9, SRC	42	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	MAPK10, MAPK9, MET, SRC	44	Link
n/a	Chagas disease	IRAK4, MAPK10, MAPK9	4	Link
n/a	Salmonella infection	MAPK10, MAPK9, ROCK2	3	Link
n/a	Toxoplasmosis	IRAK4, MAPK10, MAPK9	4	Link
n/a	Pertussis	IRAK4, MAPK10, MAPK9	4	Link
n/a	Hepatitis C	GSK3B, MAPK10, MAPK9	3	Link
	Leukemia	ABL1, CDK4, MAP2K1	48	Link
n/a	Herpes simplex infection	CDK2, MAPK10, MAPK9	32	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, ROCK2	9	Link
	Melanoma	CDK4, MAP2K1, MET	46	Link
n/a	Basal cell carcinoma	GSK3B, STK36	2	Link
	Gastric cancer	FGFR2, MET	8	Link
n/a	Prion diseases	FYN, MAP2K1	5	Link
	LADD syndrome	FGFR2, FGFR3	5	Link
	Crouzon syndrome	FGFR2, FGFR3	5	Link
	Diabetes mellitus	MAPK10, MAPK9	2	Link
n/a	Cervical cancer	CDK4, FGFR3	43	Link
	Lung cancer	CDK2, CDK4	48	Link
n/a	Viral myocarditis	ABL1, FYN	9	Link
	Scaphocephaly	FGFR2	5	Link
n/a	Saethre-Chotzen syndrome	FGFR2	5	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	5	Link
	Jackson-Weiss syndrome	FGFR2	5	Link
	Craniosynostosis	FGFR2	5	Link
	Bent bone dysplasia syndrome	FGFR2	5	Link
	Pfeiffer syndrome	FGFR2	5	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	5	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	5	Link
n/a	Glioma	CDK4	40	Link
n/a	Malignant melanoma	CDK4	40	Link
n/a	Maturity onset diabetes of the young	BLK	6	Link
	Li-Fraumeni syndrome	CHEK2	1	Link
	Breast cancer	CHEK2	1	Link
	Apert syndrome	FGFR2	5	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	5	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	3	Link
	Osteosarcoma	CHEK2	1	Link
	Colorectal cancer	FGFR3	3	Link
n/a	Multiple myeloma	FGFR3	3	Link
	Renal cell carcinoma	MET	6	Link
n/a	Cholangiocarcinoma	MET	6	Link
n/a	Epileptic encephalopathy	MAPK10	2	Link
n/a	Early infantile epileptic encephalopathy	MAPK10	2	Link
n/a	Alcoholism	MAP2K1	3	Link
	Cardiofaciocutaneous syndrome	MAP2K1	3	Link
n/a	Malaria	MET	6	Link
n/a	Autism suseptibility	MET	6	Link
n/a	Type I diabetes mellitus	PRKCQ	1	Link
	Colon cancer	SRC	42	Link
	Glycogen storage disease	PHKG2	4	Link
n/a	Cirrhosis due to liver phosphorylase kinase deficiency	PHKG2	4	Link
	Hepatocellular carcinoma	MET	6	Link
n/a	Glycogen storage diseases	PHKG2	4	Link
n/a	Noonan syndrome and related disorders	MAP2K1	3	Link
	SCID	LCK	9	Link
n/a	Hypochondroplasia	FGFR3	3	Link
n/a	Muenke syndrome	FGFR3	3	Link
n/a	Achondroplasia	FGFR3	3	Link
n/a	CATSHL syndrome	FGFR3	3	Link
n/a	Bladder cancer	FGFR3	3	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	3	Link
n/a	Nevus	FGFR3	3	Link
n/a	Spermatocytic seminoma	FGFR3	3	Link
	IRAK4 deficiency	IRAK4	3	Link
n/a	Immunodeficiencies	LCK	9	Link
n/a	Invasive pneumococcal disease	IRAK4	3	Link
n/a	Leishmaniasis	IRAK4	3	Link
n/a	Thanatophoric dysplasia	FGFR3	3	Link
n/a	Cancer progression/metastasis	FGFR4	1	Link

BioXGEM.

KIDFamMap

Allelic Variants