Allelic Variants
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There are no related allelic variants
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Number of involved diseases in the family |
75 |
Number of SRC related diseases |
4 |
All kinase in this family
SRC
Allelic Variants |
Disease Description |
Involved kinases (This family) |
Inhibitor of Involved Kinases |
Search Disease |
| Prostate cancer | BRAF, CDK2, EGFR, ERBB2, FGFR1, IGF1R, PDGFRB, RAF1 | 39 | Link | n/a | Measles | CDK2, FYN, JAK1, JAK2, JAK3, PRKCQ, TYK2 | 22 | Link | | Leukemia | ABL1, BRAF, JAK2, KIT, PDGFRB, RAF1, TGFBR1 | 22 | Link | | Melanoma | BRAF, EGFR, FGFR1, IGF1R, PDGFRB, RAF1 | 25 | Link | n/a | Hepatitis C | BRAF, EGFR, JAK1, RAF1, TYK2 | 17 | Link | n/a | Epstein-Barr virus infection | CDK2, JAK1, JAK3, LYN, TYK2 | 17 | Link | n/a | Influenza A | JAK1, JAK2, RAF1, TYK2 | 5 | Link | n/a | Epithelial cell signaling in Helicobacter pylori infection | CSK, EGFR, LYN, SRC | 40 | Link | n/a | Herpes simplex infection | CDK2, JAK1, JAK2, TYK2 | 17 | Link | n/a | Tuberculosis | JAK1, JAK2, RAF1, SRC | 40 | Link | | Lung cancer | ALK, BRAF, CDK2, EGFR | 29 | Link | | Adenocarcinoma of lung | BRAF, EGFR, ERBB2 | 15 | Link | n/a | Toxoplasmosis | JAK1, JAK2, TYK2 | 4 | Link | n/a | Viral myocarditis | ABL1, FYN | 12 | Link | | Diabetes mellitus | INSR, PRKCD | 6 | Link | | Noonan syndrome | BRAF, RAF1 | 3 | Link | n/a | Shigellosis | ABL1, SRC | 41 | Link | | Gastric cancer | EGFR, ERBB2 | 13 | Link | n/a | Glioma | EGFR, PDGFRB | 14 | Link | n/a | Pathogenic Escherichia coli infection | ABL1, FYN | 12 | Link | n/a | Cervical cancer | EGFR, ERBB2 | 13 | Link | n/a | Bladder cancer | EGFR, ERBB2 | 13 | Link | n/a | Choriocarcinoma | EGFR, ERBB2 | 13 | Link | | LEOPARD syndrome | BRAF, RAF1 | 3 | Link | n/a | Myeloproliferative disorder | JAK2, PDGFRB | 7 | Link | n/a | Immunodeficiencies | JAK3, LCK | 11 | Link | | SCID | JAK3, LCK | 11 | Link | n/a | Alcoholism | BRAF, RAF1 | 3 | Link | n/a | Leishmaniasis | JAK1, JAK2 | 4 | Link | n/a | Laryngeal cancer | EGFR | 12 | Link | n/a | Thyroid cancer | BRAF | 2 | Link | n/a | Malignant melanoma | BRAF | 2 | Link | n/a | Esophageal cancer | EGFR | 12 | Link | | Colorectal cancer | BRAF | 2 | Link | n/a | Pancreatic cancer | ERBB2 | 5 | Link | n/a | Noonan syndrome and related disorders | BRAF | 2 | Link | | Neuroblastoma | ALK | 2 | Link | | Fibrodysplasia ossificans progressiva | ACVR1 | 1 | Link | n/a | Oral cancer | EGFR | 12 | Link | n/a | Maturity onset diabetes of the young | BLK | 1 | Link | | Cardiofaciocutaneous syndrome | BRAF | 2 | Link | | Glioblastoma | ERBB2 | 5 | Link | | Endometrial Cancer | ERBB2 | 5 | Link | | Gastrointestinal stromal tumor | KIT | 1 | Link | n/a | Germ cell tumors | KIT | 1 | Link | | Piebaldism | KIT | 1 | Link | | Thrombocythemia | JAK2 | 4 | Link | n/a | Budd-Chiari syndrome | JAK2 | 4 | Link | | Myelofibrosis | JAK2 | 4 | Link | | Mast cell leukemia | KIT | 1 | Link | | Mastocytosis with associated hematologic disorder | KIT | 1 | Link | | Multiple self-healing squamous epithelioma | TGFBR1 | 1 | Link | n/a | Tyrosine kinase 2 deficiency | TYK2 | 2 | Link | n/a | Chagas disease | TGFBR1 | 1 | Link | n/a | Familial thoracic aortic aneurysm and dissection | TGFBR1 | 1 | Link | n/a | Type I diabetes mellitus | PRKCQ | 4 | Link | | Colon cancer | SRC | 36 | Link | | Loeys-Dietz syndrome | TGFBR1 | 1 | Link | | Polycythemia vera | JAK2 | 4 | Link | | Hyperinsulinemic hypoglycemia | INSR | 2 | Link | | Osteoglophonic dysplasia | FGFR1 | 7 | Link | | Trigonocephaly | FGFR1 | 7 | Link | | Hypogonadotropic hypogonadism | FGFR1 | 7 | Link | n/a | Cholangiocarcinoma | ERBB2 | 5 | Link | | Ovarian cancer | ERBB2 | 5 | Link | | Breast cancer | ERBB2 | 5 | Link | | Jackson-Weiss syndrome | FGFR1 | 7 | Link | | Kallmann syndrome | FGFR1 | 7 | Link | n/a | Leprechaunism | INSR | 2 | Link | | Rabson-Mendenhall syndrome | INSR | 2 | Link | | Insulin-like growth factor I | IGF1R | 8 | Link | n/a | Synovial sarcoma | IGF1R | 8 | Link | | Pfeiffer syndrome | FGFR1 | 7 | Link | n/a | Prion diseases | FYN | 1 | Link | n/a | Malignant pleural mesothelioma | IGF1R | 8 | Link |
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