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Example2
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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
RFZ
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Selected template
Kinase
CDK2 (PDB code: 3MY5)
[PDB]
[PDBsum]
Inhibitor
5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole (HET code: RFZ)
[PDB]
Summary of KIF 3MY5A_RFZ
(CDK2, PDB code:
3MY5
, chain A)
Number of family interactions
10
Number of family kinase
4 (
sequence conservation
) (
profiling results
)
Number of family inhibitors
8 (1 are CDK2 inhibitors)
Involved diseases
5 (
show
)
Number of family anchors
All kinase-inhibitor interactions in this family
CDK2 and 1 inhibitors