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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
3NC
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Selected template
Kinase
ROCK1 (PDB code: 3NCZ)
[PDB]
[PDBsum]
Inhibitor
Cis-4-Amino-N-(7-Chloro-1-Oxo-1,2-Dihydroisoquinolin-6-Yl)cyclohexanecarboxamide (HET code: 3NC)
[PDB]
Summary of KIF 3NCZA_3NC
(ROCK1, PDB code:
3NCZ
, chain A)
Number of family interactions
48
Number of family kinase
4 (
sequence conservation
) (
profiling results
)
Number of family inhibitors
41 (3 are PKN2 inhibitors)
Involved diseases
3 (
show
)
Number of family anchors
All kinase-inhibitor interactions in this family
PKN2 and 3 inhibitors