Protein Surface  Ribbon
Inhibitor WFE
  ATP Location
Pocket ATP NLP HAP CLP SP
Selected template
Kinase AKT1 (PDB code: 3MVH) [PDB] [PDBsum]
Inhibitor N-{[(3s)-3-Amino-1-(5-Ethyl-7h-Pyrrolo[2,3-D]pyrimidin-4-Yl)pyrrolidin-3-Yl]methyl}-2,4-Difluorobenzamide (HET code: WFE) [PDB]
 
Summary of KIF 3MVHA_WFE (AKT1, PDB code: 3MVH, chain A)
Number of family interactions 59
Number of family kinase 5 (sequence conservation) (profiling results)
Number of family inhibitors 44 (2 are ROCK2 inhibitors)
Involved diseases 23 (show)
Number of family anchors  
All kinase-inhibitor interactions in this family  ROCK2 and 2 inhibitors