BioXGEM.
KIDFamMap
Home
Example1
Example2
Statistics
Document
Contact US
Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
7 TYK2 related diseases
hsa05145
Toxoplasmosis
hsa05160
Hepatitis C
hsa05162
Measles
hsa05164
Influenza A
hsa05168
Herpes simplex infection
hsa05169
Epstein-Barr virus infection
611521
Tyrosine kinase 2 deficiency
Summary of query kinase
Query kinase
TYK2 (
P29597
)
Kinase group
TK
Number of conformation types
2
Number of structural templates
4 (
Total 139 inhibitors
)
Number of TYK2 related diseases
7 (
hsa05145
hsa05160
hsa05162
hsa05164
hsa05168
hsa05169
611521
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
1
3LXPA_IZA
(TYK2)
TK
Pyridone 6
I
9
3
20
A
3LXPA_IZA
(TYK2)
TK
Pyridone 6
I
9
3
20
9
3
20
B
3
3NZ0A_IZA
(TYK2)
TK
Pyridone 6
I
12
3
24
B
3NZ0A_IZA
(TYK2)
TK
Pyridone 6
I
12
3
24
12
3
24
B
3LXNA_MI1
(TYK2)
TK
CP690550
I
4
6
21
4
6
21
B
3NYXA_TZ1
(TYK2)
TK
AC1MOHSZ
I
3
4
14
3
4
14