KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 3D7TA_STU (PDB code: 3D7T, chain A)
Number of involved diseases in the family	99
Number of INSRR related diseases	1

All kinase in this family INSRR

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	EGFR, EPHB2, FGFR2, IGF1R, INSRR, PDPK1	42	Link
n/a	Amoebiasis	PRKACA, PRKACG, PRKCA, PRKX, PTK2	59	Link
n/a	Epstein-Barr virus infection	LYN, PRKACA, PRKACG, PRKX, SYK	11	Link
	Leukemia	ABL1, ABL2, JAK2, TGFBR1	12	Link
n/a	Vibrio cholerae infection	PRKACA, PRKACG, PRKCA, PRKX	58	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, LYN, SRC	41	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	16	Link
n/a	Tuberculosis	IRAK4, JAK2, SRC, SYK	21	Link
	Lung cancer	ALK, EGFR, PTK2, ROS1	40	Link
n/a	Cardiomyopathy	PRKACA, PRKACG, PRKX	8	Link
n/a	Influenza A	IRAK4, JAK2, PRKCA	60	Link
n/a	Prion diseases	PRKACA, PRKACG, PRKX	8	Link
n/a	Cocaine addiction	PRKACA, PRKACG, PRKX	8	Link
n/a	Bladder cancer	EGFR, FGFR3	38	Link
	Gastric cancer	EGFR, FGFR2	39	Link
n/a	Leishmaniasis	IRAK4, JAK2	11	Link
n/a	Chagas disease	IRAK4, TGFBR1	4	Link
n/a	Toxoplasmosis	IRAK4, JAK2	11	Link
n/a	Cervical cancer	EGFR, FGFR3	38	Link
n/a	Measles	IRAK4, JAK2	11	Link
	Melanoma	EGFR, IGF1R	38	Link
	Diabetes mellitus	INSR, PRKCE	12	Link
	Crouzon syndrome	FGFR2, FGFR3	8	Link
n/a	Alcoholism	NTRK2, PRKACA	10	Link
	Colon cancer	AURKA, SRC	19	Link
	LADD syndrome	FGFR2, FGFR3	8	Link
n/a	Viral myocarditis	ABL1, ABL2	9	Link
n/a	Shigellosis	ABL1, SRC	20	Link
n/a	Pathogenic Escherichia coli infection	ABL1, PRKCA	59	Link
	Scaphocephaly	FGFR2	8	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	8	Link
n/a	Saethre-Chotzen syndrome	FGFR2	8	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	8	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	8	Link
	Craniosynostosis	FGFR2	8	Link
	Jackson-Weiss syndrome	FGFR2	8	Link
	Bent bone dysplasia syndrome	FGFR2	8	Link
	Pfeiffer syndrome	FGFR2	8	Link
	Apert syndrome	FGFR2	8	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	8	Link
n/a	Glioma	EGFR	38	Link
	Adenocarcinoma of lung	EGFR	38	Link
n/a	Pituitary Dwarfism	BTK	5	Link
	Agammaglobulinemia	BTK	5	Link
n/a	Agammaglobulinemias	BTK	5	Link
n/a	Maturity onset diabetes of the young	BLK	8	Link
	Fibrodysplasia ossificans progressiva	ACVR1	3	Link
n/a	Pancreatic cancer	ACVR1B	2	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	5	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	3	Link
n/a	Laryngeal cancer	EGFR	38	Link
n/a	Hepatitis C	EGFR	38	Link
n/a	Multiple myeloma	FGFR3	7	Link
n/a	Choriocarcinoma	EGFR	38	Link
n/a	Oral cancer	EGFR	38	Link
n/a	Esophageal cancer	EGFR	38	Link
n/a	Spermatocytic seminoma	FGFR3	7	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	7	Link
n/a	Short rib-polydactyly syndorme	NEK1	3	Link
n/a	Nephronophthisis-medullary cystic kidney disease	NEK8	1	Link
n/a	Nephronophthisis	NEK8	1	Link
n/a	Myasthenic syndrome	MUSK	5	Link
n/a	Congenital myasthenic syndrome	MUSK	5	Link
n/a	Myeloproliferative disorder	JAK2	10	Link
	Thrombocythemia	JAK2	10	Link
n/a	Amyotrophic lateral sclerosis	MAP3K5	6	Link
n/a	Thyroid cancer	NTRK1	15	Link
n/a	Insensitivity to pain	NTRK1	15	Link
	Loeys-Dietz syndrome	TGFBR1	2	Link
n/a	Familial thoracic aortic aneurysm and dissection	TGFBR1	2	Link
	Multiple self-healing squamous epithelioma	TGFBR1	2	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
n/a	Pituitary tumor	PRKCA	55	Link
n/a	Medullary thyroid carcinoma	NTRK1	15	Link
n/a	Obesity	NTRK2	9	Link
n/a	Salmonella infection	PKN1	11	Link
n/a	African trypanosomiasis	PRKCA	55	Link
	Myelofibrosis	JAK2	10	Link
n/a	Budd-Chiari syndrome	JAK2	10	Link
n/a	Thanatophoric dysplasia	FGFR3	7	Link
n/a	Cancer progression/metastasis	FGFR4	3	Link
n/a	Malignant pleural mesothelioma	IGF1R	5	Link
n/a	Nevus	FGFR3	7	Link
n/a	Muenke syndrome	FGFR3	7	Link
n/a	CATSHL syndrome	FGFR3	7	Link
n/a	Achondroplasia	FGFR3	7	Link
	Colorectal cancer	FGFR3	7	Link
n/a	Hypochondroplasia	FGFR3	7	Link
n/a	Synovial sarcoma	IGF1R	5	Link
	Insulin-like growth factor I	IGF1R	5	Link
	Lymphoproliferative syndrome	ITK	6	Link
	Polycythemia vera	JAK2	10	Link
n/a	Herpes simplex infection	JAK2	10	Link
	IRAK4 deficiency	IRAK4	4	Link
n/a	Invasive pneumococcal disease	IRAK4	4	Link
n/a	Leprechaunism	INSR	5	Link
	Rabson-Mendenhall syndrome	INSR	5	Link
	Hyperinsulinemic hypoglycemia	INSR	5	Link
n/a	Pertussis	IRAK4	4	Link

BioXGEM.

KIDFamMap

Allelic Variants