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Example2
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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
B4W
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Selected template
Kinase
CHEK2 (PDB code: 2XM8)
[PDB]
[PDBsum]
Inhibitor
PI_103 (HET code: B4W)
[PDB]
Summary of KIF 2XM8A_B4W
(CHEK2, PDB code:
2XM8
, chain A)
Number of family interactions
77
Number of family kinase
12 (
sequence conservation
) (
profiling results
)
Number of family inhibitors
54 (32 are CHEK2 inhibitors)
Involved diseases
18 (
show
)
Number of family anchors
All kinase-inhibitor interactions in this family
CHEK2 and 32 inhibitors