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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Summary of query kinase
Query kinase
MATK (
P42679
)
Kinase group
TK
Number of conformation types
0
Number of structural templates
38 (
Total 10 inhibitors
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
20
2JAMA_J60
(CAMK1G)
TK
SU11652
I
50
65
32
A
2JAMA_J60
(CAMK1G)
TK
SU11652
I
50
65
32
50
65
32
A
3PJ3A_04L
(BTK)
TK
Imatinib
II
99
113
134
99
113
134
A
1U59A_STU
(ZAP70)
TK
staurosporine
I
96
80
114
96
80
114
A
2H8HA_H8H
(SRC)
TK
Saracatinib
I
91
255
126
91
255
126
A
1AQ1A_STU
(CDK2)
TK
staurosporine
I
195
76
118
195
76
118
A
1XBCA_STU
(SYK)
TK
staurosporine
I
71
72
105
71
72
105
A
3A4OX_STU
(LYN)
TK
staurosporine
I
73
70
88
73
70
88
A
1BYGA_STU
(CSK)
TK
staurosporine
I
85
72
123
85
72
123
A
1XJDA_STU
(PRKCQ)
TK
staurosporine
I
121
101
106
121
101
106
A
3CKXA_STU
(STK24)
TK
staurosporine
I
176
104
141
176
104
141
A
1YVJA_4ST
(JAK3)
TK
staurosporine
I
96
90
126
96
90
126
A
1R78A_FMD
(CDK2)
TK
4-alkynyl ox...
I
127
24
97
127
24
97
A
2DQ7X_STU
(FYN)
TK
staurosporine
I
91
74
124
91
74
124
A
2IVUA_ZD6
(RET)
TK
Vandetanib
I
83
291
121
83
291
121
A
1PKDA_UCN
(CDK2)
TK
UCN 02
I
195
67
118
195
67
118
A
2HZ4A_4ST
(ABL1)
TK
staurosporine
I
159
103
156
159
103
156
A
2IW6A_QQ2
(CDK2)
TK
2iw6
I
112
209
86
112
209
86
A
1QPDA_STU
(LCK)
TK
staurosporine
I
115
76
126
115
76
126
A
1QPJA_STU
(LCK)
TK
staurosporine
I
115
76
126
115
76
126
A
2VTTA_LZD
(CDK2)
TK
pyrazole dia...
I
158
42
111
158
42
111
B
16
3MIYA_B49
(ITK)
TK
Sunitinib
I
70
74
110
B
3MIYA_B49
(ITK)
TK
Sunitinib
I
70
74
110
70
74
110
B
3F5PA_741
(IGF1R)
TK
3-cyanoquino...
I
60
123
81
60
123
81
B
2ITWA_STU
(EGFR)
TK
staurosporine
I
80
85
106
80
85
106
B
2ITOA_IRE
(EGFR)
TK
Gefitinib
I
69
313
99
69
313
99
B
2ITYA_IRE
(EGFR)
TK
Gefitinib
I
69
313
99
69
313
99
B
1OKYA_STU
(PDPK1)
TK
staurosporine
I
179
67
109
179
67
109
B
3D7TA_STU
(CSK)
TK
staurosporine
I
70
68
99
70
68
99
B
2ITZA_IRE
(EGFR)
TK
Gefitinib
I
69
313
99
69
313
99
B
1OKZA_UCN
(PDPK1)
TK
UCN 02
I
179
60
109
179
60
109
B
3LCSA_STU
(ALK)
TK
staurosporine
I
73
100
109
73
100
109
B
2XB7A_GUI
(ALK)
TK
NVP-TAE684
I
71
66
107
71
66
107
B
3EKNA_GS3
(INSR)
TK
pyrrolo[2,3-...
I
90
215
127
90
215
127
B
2ITQA_STU
(EGFR)
TK
staurosporine
I
80
85
106
80
85
106
B
2PE2A_464
(PDPK1)
TK
Indolinone b...
I
134
156
104
134
156
104
B
2VWUA_7X1
(EPHB4)
TK
Chlorobenzod...
I
77
287
111
77
287
111
B
2ITUA_STU
(EGFR)
TK
staurosporine
I
80
85
106
80
85
106
E
2
3G0EA_B49
(KIT)
TK
Sunitinib
I
37
40
78
E
3G0EA_B49
(KIT)
TK
Sunitinib
I
37
40
78
37
40
78
E
3G0FA_B49
(KIT)
TK
Sunitinib
I
37
40
78
37
40
78