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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
306
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Selected template
Kinase
CHEK1 (PDB code: 2HY0)
[PDB]
[PDBsum]
Inhibitor
AMG_706 (HET code: 306)
[PDB]
Summary of KIF 2HY0A_306
(CHEK1, PDB code:
2HY0
, chain A)
Number of family interactions
113
Number of family kinase
23 (
sequence conservation
) (
profiling results
)
Number of family inhibitors
80 (5 are PRKCZ inhibitors)
Involved diseases
49 (
show
)
Number of family anchors
All kinase-inhibitor interactions in this family
PRKCZ and 5 inhibitors