Protein Surface  Ribbon
Inhibitor
  ATP Location
Pocket ATP NLP HAP CLP SP
16 BRAF related diseases 
H00032Thyroid cancer
H00038Malignant melanoma
H00523Noonan syndrome and related disorders
hsa05034Alcoholism
hsa05160Hepatitis C
hsa05215Prostate cancer
hsa05218Melanoma
hsa05220Chronic myeloid leukemia
hsa05221Acute myeloid leukemia
211980Adenocarcinoma of lung, somatic
115150Cardiofaciocutaneous syndrome
OMIM
(164757)		Colorectal cancer, somatic
613707LEOPARD syndrome 3
OMIM
(164757)		Non-small cell lung cancer, somatic
OMIM
(164757)		Melanoma, malignant, somatic
613706Noonan syndrome 7
Summary of query kinase
Query kinase BRAF (P15056)
Kinase group TKL
Number of conformation types 2 
Number of structural templates 18 (Total 508 inhibitors)
Number of BRAF related diseases 16 (H00032 H00038 H00523 hsa05034 hsa05160 hsa05215 hsa05218 hsa05220 ...) 
Number of allelic variants 25 (A246P D594G D638E E501G E501K G464E G466V G469A G469E G469R ...) 
Select
Template		 Comformation
Type 		 No. of
Templates		 Representative
Template		 Kinase
Group		 Representative
Inhibitor		 Inhibitor
Type		 No. of
Kinases		 No. of
Inhibitors		 No. of
Diseases
A 13 3C4CA_324
(BRAF)		 TKL PLX4720 I 35 5 58
E 5 1UWHA_BAX
(BRAF)		 TKL Sorafenib II 19 39 35