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KIDFamMap
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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
4 SRC related diseases
hsa05120
Epithelial cell signaling in Helicobacter pylori infection
hsa05131
Shigellosis
hsa05152
Tuberculosis
OMIM
(190090)
Colon cancer, advanced
Summary of query kinase
Query kinase
SRC (
P12931
)
Kinase group
TK
Number of conformation types
2
Number of structural templates
8 (
Total 1829 inhibitors
)
Number of SRC related diseases
4 (
hsa05120
hsa05131
hsa05152
OMIM:190090
)
Number of allelic variants
1 (
Q531X
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
7
2H8HA_H8H
(SRC)
TK
Saracatinib
I
91
255
126
A
2H8HA_H8H
(SRC)
TK
Saracatinib
I
91
255
126
91
255
126
A
1Y57A_MPZ
(SRC)
TK
MPZ
I
42
155
94
42
155
94
A
1YOLA_S03
(SRC)
TK
QGPSFIYTQAON...
I
30
114
75
30
114
75
A
1KSWA_NBS
(SRC)
TK
adenosine te...
I
24
12
76
24
12
76
A
2SRCA_ANP
(SRC)
TK
Phosphoamino...
I
24
12
76
24
12
76
A
2BDJA_HET
(SRC)
TK
AP-23464
I
8
26
23
8
26
23
A
2BDFA_24A
(SRC)
TK
24A
I
3
5
12
3
5
12
B
1
1YOMA_P01
(SRC)
TK
Lopac0_000938
I
27
95
57
B
1YOMA_P01
(SRC)
TK
Lopac0_000938
I
27
95
57
27
95
57