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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
2 CSF1R related diseases
H00028
Choriocarcinoma
221820
Leukoencephalopathy, diffuse hereditary, with spheroids
Summary of query kinase
Query kinase
CSF1R (
P07333
)
Kinase group
TK
Number of conformation types
2
Number of structural templates
9 (
Total 476 inhibitors
)
Number of CSF1R related diseases
2 (
H00028
221820
)
Number of allelic variants
4 (
D837Y
E633K
I794T
M875T
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
4
3LCDA_BDY
(CSF1R)
TK
Sunitinib
I
23
168
86
A
3LCDA_BDY
(CSF1R)
TK
Sunitinib
I
23
168
86
23
168
86
A
3BEAA_IXH
(CSF1R)
TK
Pyrido[2,3-d...
I
19
77
69
19
77
69
A
2I0YA_5CN
(CSF1R)
TK
5CN
I
1
28
2
1
28
2
A
2I1MA_5CN
(CSF1R)
TK
5CN
I
1
28
2
1
28
2
E
5
3KRJA_KRJ
(CSF1R)
TK
AMG_706
I
11
49
23
E
3KRJA_KRJ
(CSF1R)
TK
AMG_706
I
11
49
23
11
49
23
E
3KRLA_KRL
(CSF1R)
TK
5-Cyano-N-[4...
I
11
88
23
11
88
23
E
3DPKA_8C5
(CSF1R)
TK
Pyrido[2,3-d...
I
7
57
17
7
57
17
E
3LCOA_LC0
(CSF1R)
TK
LC0
II
2
9
3
2
9
3
E
2I0VA_6C3
(CSF1R)
TK
Quinolone, 2
I
1
2
2
1
2
2