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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
5 CDK2 related diseases
hsa05162
Measles
hsa05168
Herpes simplex infection
hsa05169
Epstein-Barr virus infection
hsa05215
Prostate cancer
hsa05222
Small cell lung cancer
Summary of query compound
Query compound
Staurosporine
Molecular Formula
C
28
H
26
N
4
O
3
(Molecular Weight : 466.531 [g/mol])
Number of conformation types
2
Number of structural templates
36 (
Total target kinases
)
Number of CDK2 related diseases
5 (
hsa05162
hsa05168
hsa05169
hsa05215
hsa05222
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
25
1AQ1A_STU
(CDK2)
CMGC
staurosporine
I
195
76
118
A
1AQ1A_STU
(CDK2)
CMGC
staurosporine
I
195
76
118
195
76
118
A
1SM2A_STU
(ITK)
TK
staurosporine
I
99
104
128
99
104
128
A
1BYGA_STU
(CSK)
TK
staurosporine
I
85
72
123
85
72
123
A
3FMEA_STU
(MAP2K6)
STE
staurosporine
I
28
15
20
28
15
20
A
1SNUA_STU
(ITK)
TK
staurosporine
I
99
104
128
99
104
128
A
3HMOA_STU
(TTK)
Other
staurosporine
I
27
50
20
27
50
20
A
1U59A_STU
(ZAP70)
TK
staurosporine
I
96
80
114
96
80
114
A
1NVRA_STU
(CHEK1)
CAMK
staurosporine
I
179
71
79
179
71
79
A
1NXKA_STU
(MAPKAPK2)
CAMK
staurosporine
I
110
67
51
110
67
51
A
1XBCA_STU
(SYK)
TK
staurosporine
I
71
72
105
71
72
105
A
1XJDA_STU
(PRKCQ)
AGC
staurosporine
I
121
101
106
121
101
106
A
3A4OX_STU
(LYN)
TK
staurosporine
I
73
70
88
73
70
88
A
1YHSA_STU
(PIM1)
CAMK
staurosporine
I
78
64
50
78
64
50
A
1Q3DA_STU
(GSK3B)
CMGC
staurosporine
I
115
71
61
115
71
61
A
2BUJA_STU
(STK16)
Other
staurosporine
I
4
10
5
4
10
5
A
1QPDA_STU
(LCK)
TK
staurosporine
I
115
76
126
115
76
126
A
2DQ7X_STU
(FYN)
TK
staurosporine
I
91
74
124
91
74
124
A
3CKXA_STU
(STK24)
STE
staurosporine
I
176
104
141
176
104
141
A
1QPJA_STU
(LCK)
TK
staurosporine
I
115
76
126
115
76
126
A
2HW7A_STU
(MKNK2)
CAMK
staurosporine
I
28
55
16
28
55
16
A
1NVQA_UCN
(CHEK1)
CAMK
UCN 02
I
179
65
79
179
65
79
A
1PKDA_UCN
(CDK2)
CMGC
UCN 02
I
195
67
118
195
67
118
A
2HZ4A_4ST
(ABL1)
TK
staurosporine
I
159
103
156
159
103
156
A
1YVJA_4ST
(JAK3)
TK
staurosporine
I
96
90
126
96
90
126
A
2HY81_1ST
(PAK1)
STE
UCN 02
I
58
20
75
58
20
75
B
11
3D7TA_STU
(CSK)
TK
staurosporine
I
70
68
99
B
3D7TA_STU
(CSK)
TK
staurosporine
I
70
68
99
70
68
99
B
2ITQA_STU
(EGFR)
TK
staurosporine
I
80
85
106
80
85
106
B
3LCSA_STU
(ALK)
TK
staurosporine
I
73
100
109
73
100
109
B
1WVYA_STU
(DAPK1)
CAMK
staurosporine
I
83
23
55
83
23
55
B
2ITUA_STU
(EGFR)
TK
staurosporine
I
80
85
106
80
85
106
B
2ITWA_STU
(EGFR)
TK
staurosporine
I
80
85
106
80
85
106
B
1OKYA_STU
(PDPK1)
AGC
staurosporine
I
179
67
109
179
67
109
B
3BKBA_STU
(FES)
TK
staurosporine
I
131
107
138
131
107
138
B
3CBLA_STU
(FES)
TK
staurosporine
I
131
107
138
131
107
138
B
3CD3A_STU
(FES)
TK
staurosporine
I
131
107
138
131
107
138
B
1OKZA_UCN
(PDPK1)
AGC
UCN 02
I
179
60
109
179
60
109