BioXGEM.
KIDFamMap
Home
Example1
Example2
Statistics
Document
Contact US
Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Summary of query kinase
Query kinase
MAPKAPK2 (
P49137
)
Kinase group
CAMK
Number of conformation types
2
Number of structural templates
19 (
Total 466 inhibitors
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
17
1NXKA_STU
(MAPKAPK2)
CAMK
staurosporine
I
110
67
51
A
1NXKA_STU
(MAPKAPK2)
CAMK
staurosporine
I
110
67
51
110
67
51
A
3M2WA_L8I
(MAPKAPK2)
CAMK
Sunitinib
I
84
90
47
84
90
47
A
3A2CA_PDY
(MAPKAPK2)
CAMK
6-(4-methoxy...
I
32
39
21
32
39
21
A
2JBPA_P4O
(MAPKAPK2)
CAMK
2jbo
I
18
130
30
18
130
30
A
2JBOA_P4O
(MAPKAPK2)
CAMK
2jbo
I
18
130
30
18
130
30
A
3R2YA_P4O
(MAPKAPK2)
CAMK
2jbo
I
18
130
30
18
130
30
A
1NY3A_ADP
(MAPKAPK2)
CAMK
Adenosine-5'...
I
17
7
17
17
7
17
A
3KGAA_LX9
(MAPKAPK2)
CAMK
LX9
I
14
42
21
14
42
21
A
2PZYA_B18
(MAPKAPK2)
CAMK
carboline an...
I
11
56
15
11
56
15
A
3M42A_HGF
(MAPKAPK2)
CAMK
SB_431542
I
5
61
9
5
61
9
A
3R2BA_05B
(MAPKAPK2)
CAMK
SB_431542
I
4
58
5
4
58
5
A
3KC3A_MK2
(MAPKAPK2)
CAMK
N~4~-[7-(1-B...
I
4
13
20
4
13
20
A
3FYKX_B98
(MAPKAPK2)
CAMK
DB07431
I
4
20
0
4
20
0
A
3FPMA_793
(MAPKAPK2)
CAMK
DB07234
I
3
19
0
3
19
0
A
3FYJX_B97
(MAPKAPK2)
CAMK
VX_680
I
2
14
6
2
14
6
A
3KA0A_MK3
(MAPKAPK2)
CAMK
thieno[2,3-c...
I
1
1
0
1
1
0
A
3R30A_CD2
(MAPKAPK2)
CAMK
1-(2-Aminoet...
I
1
5
0
1
5
0
B
2
3GOKA_P4O
(MAPKAPK2)
CAMK
2jbo
I
20
134
35
B
3GOKA_P4O
(MAPKAPK2)
CAMK
2jbo
I
20
134
35
20
134
35
B
2P3GX_F10
(MAPKAPK2)
CAMK
Pyrrolopyrid...
I
8
89
10
8
89
10